Reversal of P‐Glycoprotein‐mediated Paclitaxel Resistance by New Synthetic Isoprenoids in Human Bladder Cancer Cell Line

We isolated a paclitaxel‐resistant cell line (KK47/TX30) from a human bladder cancer cell line (KK47/WT) in order to investigate the mechanism of and reversal agents for paclitaxel resistance. KK47/TX30 cells exhibited 700‐fold resistance to paclitaxel and cross‐resistance to vinca alkaloids and top...

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Detalles Bibliográficos
Autores principales: Enokida, Hideki, Gotanda, Takenari, Oku, Shoichi, Imazono, Yoshiharu, Kubo, Hiroyuki, Hanada, Toshikatsu, Suzuki, Shigenori, Inomata, Kouhei, Kishiye, Takao, Tahara, Yoshiyuki, Nishiyama, Kenryu, Nakagawa, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927134/
https://www.ncbi.nlm.nih.gov/pubmed/12359058
http://dx.doi.org/10.1111/j.1349-7006.2002.tb02481.x

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