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MCU-knockdown attenuates high glucose-induced inflammation through regulating MAPKs/NF-κB pathways and ROS production in HepG2 cells

Mitochondrial Ca(2+) is a key regulator of organelle physiology and the excessive increase in mitochondrial calcium is associated with the oxidative stress. In the present study, we investigated the molecular mechanisms linking mitochondrial calcium to inflammatory and coagulative responses in hepat...

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Detalles Bibliográficos
Autores principales: Panahi, Ghodratollah, Pasalar, Parvin, Zare, Mina, Rizzuto, Rosario, Meshkani, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927441/
https://www.ncbi.nlm.nih.gov/pubmed/29709004
http://dx.doi.org/10.1371/journal.pone.0196580