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Rho GTPases, their post-translational modifications, disease-associated mutations and pharmacological inhibitors
The 20 members of the Rho GTPase family are key regulators of a wide-variety of biological activities. In response to activation, they signal via downstream effector proteins to induce dynamic alterations in the organization of the actomyosin cytoskeleton. In this review, post-translational modifica...
Autor principal: | Olson, Michael F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927519/ https://www.ncbi.nlm.nih.gov/pubmed/27548350 http://dx.doi.org/10.1080/21541248.2016.1218407 |
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