Interleukin 10 (IL10) proximal promoter polymorphisms beyond clinical response in classical Hodgkin lymphoma: Exploring the basis for the genetic control of the tumor microenvironment

Interleukin-10 (IL10) is an immune regulatory cytokine. Single nucleotide polymorphisms (SNPs) in IL10 promoter have been associated with prognosis in adult classical Hodgkin lymphoma (cHL). We analyzed IL10 SNPs −1082 and −592 in respect of therapy response, gene expression and tumor microenvironme...

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Detalles Bibliográficos
Autores principales: Vera-Lozada, Gabriela, Minnicelli, Carolina, Segges, Priscilla, Stefanoff, Gustavo, Kristcevic, Flavia, Ezpeleta, Joaquin, Tapia, Elizabeth, Niedobitek, Gerald, Barros, Mário Henrique M., Hassan, Rocio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927538/
https://www.ncbi.nlm.nih.gov/pubmed/29721365
http://dx.doi.org/10.1080/2162402X.2017.1389821

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