Increased immune infiltration and chemokine receptor expression in head and neck epithelial tumors after neoadjuvant immunotherapy with the IRX-2 regimen

IRX-2 is an injectable cancer immunotherapy composed of cytokines purified from stimulated normal-donor peripheral blood mononuclear cells. In a phase 2a trial (n = 27), neoadjuvant IRX-2 significantly increased lymphocyte infiltration (LI) into resected head and neck tumors and was associated with...

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Detalles Bibliográficos
Autores principales: Berinstein, Neil L., McNamara, Michael, Nguyen, Ariane, Egan, James, Wolf, Gregory T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927542/
https://www.ncbi.nlm.nih.gov/pubmed/29721379
http://dx.doi.org/10.1080/2162402X.2017.1423173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927542/
https://www.ncbi.nlm.nih.gov/pubmed/29721379
http://dx.doi.org/10.1080/2162402X.2017.1423173

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