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Rheumatic heart disease in pregnancy: a report of 2 cases

Pregnant women with severe mitral stenosis tend to experience clinical decompensation with approximately 50% mortality and they may experience adverse effects of the medication they are taking, notably congenital malformations from warfarin exposure. Corrective heart surgery may increase the risk of...

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Autores principales: Ziruma, Asaph, Nyakanda, Munyaradzi Innocent, Muyotcha, Annie Fungai, Hove, Fungisai Nyarai, Madziyire, Mugove Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927558/
https://www.ncbi.nlm.nih.gov/pubmed/29721129
http://dx.doi.org/10.11604/pamj.2017.28.298.14159
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author Ziruma, Asaph
Nyakanda, Munyaradzi Innocent
Muyotcha, Annie Fungai
Hove, Fungisai Nyarai
Madziyire, Mugove Gerald
author_facet Ziruma, Asaph
Nyakanda, Munyaradzi Innocent
Muyotcha, Annie Fungai
Hove, Fungisai Nyarai
Madziyire, Mugove Gerald
author_sort Ziruma, Asaph
collection PubMed
description Pregnant women with severe mitral stenosis tend to experience clinical decompensation with approximately 50% mortality and they may experience adverse effects of the medication they are taking, notably congenital malformations from warfarin exposure. Corrective heart surgery may increase the risk of pregnancy loss. We present 2 cases of RHD in pregnancy. The first case was a 27-year-old patient in her first pregnancy with severe mitral stenosis. Caesarean section was done for foetal distress and she delivered a small for gestational age baby. She was closely monitored postpartum and was stable on discharge. She presented with supraventricular tachycardia and died in the coronary care unit 4 weeks postpartum. The second case was a 28-year-old who was on warfarin for a mechanical mitral valve. A foetal anomaly scan done at 20 weeks showed severe congenital malformations which were not compatible with extra-uterine life. The pregnancy was terminated and she recovered well. The first case illustrates the significant mortality risk with uncorrected severe rheumatic heart disease. The second case highlights the risks of warfarin on the foetus and the need to avoid mechanical heart valves if possible in young women. RHD patients require preconception counselling so they can make informed reproductive choices.
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spelling pubmed-59275582018-05-02 Rheumatic heart disease in pregnancy: a report of 2 cases Ziruma, Asaph Nyakanda, Munyaradzi Innocent Muyotcha, Annie Fungai Hove, Fungisai Nyarai Madziyire, Mugove Gerald Pan Afr Med J Case Report Pregnant women with severe mitral stenosis tend to experience clinical decompensation with approximately 50% mortality and they may experience adverse effects of the medication they are taking, notably congenital malformations from warfarin exposure. Corrective heart surgery may increase the risk of pregnancy loss. We present 2 cases of RHD in pregnancy. The first case was a 27-year-old patient in her first pregnancy with severe mitral stenosis. Caesarean section was done for foetal distress and she delivered a small for gestational age baby. She was closely monitored postpartum and was stable on discharge. She presented with supraventricular tachycardia and died in the coronary care unit 4 weeks postpartum. The second case was a 28-year-old who was on warfarin for a mechanical mitral valve. A foetal anomaly scan done at 20 weeks showed severe congenital malformations which were not compatible with extra-uterine life. The pregnancy was terminated and she recovered well. The first case illustrates the significant mortality risk with uncorrected severe rheumatic heart disease. The second case highlights the risks of warfarin on the foetus and the need to avoid mechanical heart valves if possible in young women. RHD patients require preconception counselling so they can make informed reproductive choices. The African Field Epidemiology Network 2017-12-08 /pmc/articles/PMC5927558/ /pubmed/29721129 http://dx.doi.org/10.11604/pamj.2017.28.298.14159 Text en © Asaph Ziruma et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ziruma, Asaph
Nyakanda, Munyaradzi Innocent
Muyotcha, Annie Fungai
Hove, Fungisai Nyarai
Madziyire, Mugove Gerald
Rheumatic heart disease in pregnancy: a report of 2 cases
title Rheumatic heart disease in pregnancy: a report of 2 cases
title_full Rheumatic heart disease in pregnancy: a report of 2 cases
title_fullStr Rheumatic heart disease in pregnancy: a report of 2 cases
title_full_unstemmed Rheumatic heart disease in pregnancy: a report of 2 cases
title_short Rheumatic heart disease in pregnancy: a report of 2 cases
title_sort rheumatic heart disease in pregnancy: a report of 2 cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927558/
https://www.ncbi.nlm.nih.gov/pubmed/29721129
http://dx.doi.org/10.11604/pamj.2017.28.298.14159
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