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Transcription pausing: biological significance of thermal fluctuations biased by repetitive genomic sequences

Transcription of DNA by RNA polymerase (RNAP) takes place in a cell environment dominated by thermal fluctuations. How are transcription reactions including initiation, elongation, and termination on genomic DNA so well-controlled during such fluctuations? A recent statistical mechanical approach us...

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Detalles Bibliográficos
Autores principales:	Imashimizu, Masahiko, Lukatsky, David B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2017
Materias:	Point-of-View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927657/ https://www.ncbi.nlm.nih.gov/pubmed/29105534 http://dx.doi.org/10.1080/21541264.2017.1393492

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