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Distinct protein signatures of acute myeloid leukemia bone marrow-derived stromal cells are prognostic for patient survival

Mesenchymal stromal cells (MSC) support acute myeloid leukemia (AML) cell survival in the bone marrow (BM) microenvironment. Protein expression profiles of AML-derived MSC are unknown. Reverse phase protein array analysis was performed to compare expression of 151 proteins from AML-MSC (n=106) with...

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Detalles Bibliográficos
Autores principales: Kornblau, Steven M., Ruvolo, Peter P., Wang, Rui-Yu, Battula, V. Lokesh, Shpall, Elizabeth J., Ruvolo, Vivian R., McQueen, Teresa, Qui, YiHua, Zeng, Zhihong, Pierce, Sherry, Jacamo, Rodrigo, Yoo, Suk-Young, Le, Phuong M., Sun, Jeffrey, Hail, Numsen, Konopleva, Marina, Andreeff, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927978/
https://www.ncbi.nlm.nih.gov/pubmed/29545342
http://dx.doi.org/10.3324/haematol.2017.172429