Cargando…

Salient features and outcomes of Charcot foot – An often-overlooked diabetic complication: A 17-year-experience at a diabetic center in Bangkok

BACKGROUND: Charcot foot is a rare but a serious diabetic condition. Recognition of this often overlooked condition to provide timely and proper management is important for a better prognosis. Limited data on Charcot foot was available in Asians. AIMS: The aim of this study is to describe salient fe...

Descripción completa

Detalles Bibliográficos
Autores principales: Thewjitcharoen, Yotsapon, Sripatpong, Jeeraphan, Parksook, Wyn, Krittiyawong, Sirinate, Porramatikul, Sriurai, Srikummoon, Taweesak, Mahaudomporn, Somkiet, Nakasatien, Soontaree, Himathongkam, Thep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928004/
https://www.ncbi.nlm.nih.gov/pubmed/29725580
http://dx.doi.org/10.1016/j.jcte.2018.01.001
_version_ 1783319152871604224
author Thewjitcharoen, Yotsapon
Sripatpong, Jeeraphan
Parksook, Wyn
Krittiyawong, Sirinate
Porramatikul, Sriurai
Srikummoon, Taweesak
Mahaudomporn, Somkiet
Nakasatien, Soontaree
Himathongkam, Thep
author_facet Thewjitcharoen, Yotsapon
Sripatpong, Jeeraphan
Parksook, Wyn
Krittiyawong, Sirinate
Porramatikul, Sriurai
Srikummoon, Taweesak
Mahaudomporn, Somkiet
Nakasatien, Soontaree
Himathongkam, Thep
author_sort Thewjitcharoen, Yotsapon
collection PubMed
description BACKGROUND: Charcot foot is a rare but a serious diabetic condition. Recognition of this often overlooked condition to provide timely and proper management is important for a better prognosis. Limited data on Charcot foot was available in Asians. AIMS: The aim of this study is to describe salient features and outcomes of Charcot foot in Thai patients. METHOD: We presented our experience of 40 cases of Charcot foot patients who were treated from 2000 to 2016 at Theptarin Hospital, Bangkok, Thailand. RESULTS: A total of 40 Charcot foot patients were identified (13 acute, 27 chronic; mean age 58.7 ± 10.2 years; duration of diabetes 18.0 ± 8.8 years; T2DM 95%). The average serum HbA(1c) level was 9.2 ± 1.9%. While acute Charcot foot was frequently misdiagnosed as cellulitis in almost one-third of patients, osteomyelitis was a leading cause of misdiagnosis in 15% of chronic Charcot foot patients. Ulcer-free rate at 6 and 12 months were observed in 60% and 58% of patients, respectively. The mortality rate was 13% during a median follow-up period of 57 months. Only 61% of the patients resumed walking normally while almost one-fourth of them were wheelchair-bound. CONCLUSIONS: Charcot foot in Thai patients mainly developed in long-standing poorly controlled type 2 diabetes with neuropathy, and presented late in the course of the disease. It was often misdiagnosed resulting in improper management and poor outcome which included amputation.
format Online
Article
Text
id pubmed-5928004
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-59280042018-05-03 Salient features and outcomes of Charcot foot – An often-overlooked diabetic complication: A 17-year-experience at a diabetic center in Bangkok Thewjitcharoen, Yotsapon Sripatpong, Jeeraphan Parksook, Wyn Krittiyawong, Sirinate Porramatikul, Sriurai Srikummoon, Taweesak Mahaudomporn, Somkiet Nakasatien, Soontaree Himathongkam, Thep J Clin Transl Endocrinol Research Paper BACKGROUND: Charcot foot is a rare but a serious diabetic condition. Recognition of this often overlooked condition to provide timely and proper management is important for a better prognosis. Limited data on Charcot foot was available in Asians. AIMS: The aim of this study is to describe salient features and outcomes of Charcot foot in Thai patients. METHOD: We presented our experience of 40 cases of Charcot foot patients who were treated from 2000 to 2016 at Theptarin Hospital, Bangkok, Thailand. RESULTS: A total of 40 Charcot foot patients were identified (13 acute, 27 chronic; mean age 58.7 ± 10.2 years; duration of diabetes 18.0 ± 8.8 years; T2DM 95%). The average serum HbA(1c) level was 9.2 ± 1.9%. While acute Charcot foot was frequently misdiagnosed as cellulitis in almost one-third of patients, osteomyelitis was a leading cause of misdiagnosis in 15% of chronic Charcot foot patients. Ulcer-free rate at 6 and 12 months were observed in 60% and 58% of patients, respectively. The mortality rate was 13% during a median follow-up period of 57 months. Only 61% of the patients resumed walking normally while almost one-fourth of them were wheelchair-bound. CONCLUSIONS: Charcot foot in Thai patients mainly developed in long-standing poorly controlled type 2 diabetes with neuropathy, and presented late in the course of the disease. It was often misdiagnosed resulting in improper management and poor outcome which included amputation. Elsevier 2018-01-31 /pmc/articles/PMC5928004/ /pubmed/29725580 http://dx.doi.org/10.1016/j.jcte.2018.01.001 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Paper
Thewjitcharoen, Yotsapon
Sripatpong, Jeeraphan
Parksook, Wyn
Krittiyawong, Sirinate
Porramatikul, Sriurai
Srikummoon, Taweesak
Mahaudomporn, Somkiet
Nakasatien, Soontaree
Himathongkam, Thep
Salient features and outcomes of Charcot foot – An often-overlooked diabetic complication: A 17-year-experience at a diabetic center in Bangkok
title Salient features and outcomes of Charcot foot – An often-overlooked diabetic complication: A 17-year-experience at a diabetic center in Bangkok
title_full Salient features and outcomes of Charcot foot – An often-overlooked diabetic complication: A 17-year-experience at a diabetic center in Bangkok
title_fullStr Salient features and outcomes of Charcot foot – An often-overlooked diabetic complication: A 17-year-experience at a diabetic center in Bangkok
title_full_unstemmed Salient features and outcomes of Charcot foot – An often-overlooked diabetic complication: A 17-year-experience at a diabetic center in Bangkok
title_short Salient features and outcomes of Charcot foot – An often-overlooked diabetic complication: A 17-year-experience at a diabetic center in Bangkok
title_sort salient features and outcomes of charcot foot – an often-overlooked diabetic complication: a 17-year-experience at a diabetic center in bangkok
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928004/
https://www.ncbi.nlm.nih.gov/pubmed/29725580
http://dx.doi.org/10.1016/j.jcte.2018.01.001
work_keys_str_mv AT thewjitcharoenyotsapon salientfeaturesandoutcomesofcharcotfootanoftenoverlookeddiabeticcomplicationa17yearexperienceatadiabeticcenterinbangkok
AT sripatpongjeeraphan salientfeaturesandoutcomesofcharcotfootanoftenoverlookeddiabeticcomplicationa17yearexperienceatadiabeticcenterinbangkok
AT parksookwyn salientfeaturesandoutcomesofcharcotfootanoftenoverlookeddiabeticcomplicationa17yearexperienceatadiabeticcenterinbangkok
AT krittiyawongsirinate salientfeaturesandoutcomesofcharcotfootanoftenoverlookeddiabeticcomplicationa17yearexperienceatadiabeticcenterinbangkok
AT porramatikulsriurai salientfeaturesandoutcomesofcharcotfootanoftenoverlookeddiabeticcomplicationa17yearexperienceatadiabeticcenterinbangkok
AT srikummoontaweesak salientfeaturesandoutcomesofcharcotfootanoftenoverlookeddiabeticcomplicationa17yearexperienceatadiabeticcenterinbangkok
AT mahaudompornsomkiet salientfeaturesandoutcomesofcharcotfootanoftenoverlookeddiabeticcomplicationa17yearexperienceatadiabeticcenterinbangkok
AT nakasatiensoontaree salientfeaturesandoutcomesofcharcotfootanoftenoverlookeddiabeticcomplicationa17yearexperienceatadiabeticcenterinbangkok
AT himathongkamthep salientfeaturesandoutcomesofcharcotfootanoftenoverlookeddiabeticcomplicationa17yearexperienceatadiabeticcenterinbangkok