Cargando…
Salient features and outcomes of Charcot foot – An often-overlooked diabetic complication: A 17-year-experience at a diabetic center in Bangkok
BACKGROUND: Charcot foot is a rare but a serious diabetic condition. Recognition of this often overlooked condition to provide timely and proper management is important for a better prognosis. Limited data on Charcot foot was available in Asians. AIMS: The aim of this study is to describe salient fe...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928004/ https://www.ncbi.nlm.nih.gov/pubmed/29725580 http://dx.doi.org/10.1016/j.jcte.2018.01.001 |
_version_ | 1783319152871604224 |
---|---|
author | Thewjitcharoen, Yotsapon Sripatpong, Jeeraphan Parksook, Wyn Krittiyawong, Sirinate Porramatikul, Sriurai Srikummoon, Taweesak Mahaudomporn, Somkiet Nakasatien, Soontaree Himathongkam, Thep |
author_facet | Thewjitcharoen, Yotsapon Sripatpong, Jeeraphan Parksook, Wyn Krittiyawong, Sirinate Porramatikul, Sriurai Srikummoon, Taweesak Mahaudomporn, Somkiet Nakasatien, Soontaree Himathongkam, Thep |
author_sort | Thewjitcharoen, Yotsapon |
collection | PubMed |
description | BACKGROUND: Charcot foot is a rare but a serious diabetic condition. Recognition of this often overlooked condition to provide timely and proper management is important for a better prognosis. Limited data on Charcot foot was available in Asians. AIMS: The aim of this study is to describe salient features and outcomes of Charcot foot in Thai patients. METHOD: We presented our experience of 40 cases of Charcot foot patients who were treated from 2000 to 2016 at Theptarin Hospital, Bangkok, Thailand. RESULTS: A total of 40 Charcot foot patients were identified (13 acute, 27 chronic; mean age 58.7 ± 10.2 years; duration of diabetes 18.0 ± 8.8 years; T2DM 95%). The average serum HbA(1c) level was 9.2 ± 1.9%. While acute Charcot foot was frequently misdiagnosed as cellulitis in almost one-third of patients, osteomyelitis was a leading cause of misdiagnosis in 15% of chronic Charcot foot patients. Ulcer-free rate at 6 and 12 months were observed in 60% and 58% of patients, respectively. The mortality rate was 13% during a median follow-up period of 57 months. Only 61% of the patients resumed walking normally while almost one-fourth of them were wheelchair-bound. CONCLUSIONS: Charcot foot in Thai patients mainly developed in long-standing poorly controlled type 2 diabetes with neuropathy, and presented late in the course of the disease. It was often misdiagnosed resulting in improper management and poor outcome which included amputation. |
format | Online Article Text |
id | pubmed-5928004 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-59280042018-05-03 Salient features and outcomes of Charcot foot – An often-overlooked diabetic complication: A 17-year-experience at a diabetic center in Bangkok Thewjitcharoen, Yotsapon Sripatpong, Jeeraphan Parksook, Wyn Krittiyawong, Sirinate Porramatikul, Sriurai Srikummoon, Taweesak Mahaudomporn, Somkiet Nakasatien, Soontaree Himathongkam, Thep J Clin Transl Endocrinol Research Paper BACKGROUND: Charcot foot is a rare but a serious diabetic condition. Recognition of this often overlooked condition to provide timely and proper management is important for a better prognosis. Limited data on Charcot foot was available in Asians. AIMS: The aim of this study is to describe salient features and outcomes of Charcot foot in Thai patients. METHOD: We presented our experience of 40 cases of Charcot foot patients who were treated from 2000 to 2016 at Theptarin Hospital, Bangkok, Thailand. RESULTS: A total of 40 Charcot foot patients were identified (13 acute, 27 chronic; mean age 58.7 ± 10.2 years; duration of diabetes 18.0 ± 8.8 years; T2DM 95%). The average serum HbA(1c) level was 9.2 ± 1.9%. While acute Charcot foot was frequently misdiagnosed as cellulitis in almost one-third of patients, osteomyelitis was a leading cause of misdiagnosis in 15% of chronic Charcot foot patients. Ulcer-free rate at 6 and 12 months were observed in 60% and 58% of patients, respectively. The mortality rate was 13% during a median follow-up period of 57 months. Only 61% of the patients resumed walking normally while almost one-fourth of them were wheelchair-bound. CONCLUSIONS: Charcot foot in Thai patients mainly developed in long-standing poorly controlled type 2 diabetes with neuropathy, and presented late in the course of the disease. It was often misdiagnosed resulting in improper management and poor outcome which included amputation. Elsevier 2018-01-31 /pmc/articles/PMC5928004/ /pubmed/29725580 http://dx.doi.org/10.1016/j.jcte.2018.01.001 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Research Paper Thewjitcharoen, Yotsapon Sripatpong, Jeeraphan Parksook, Wyn Krittiyawong, Sirinate Porramatikul, Sriurai Srikummoon, Taweesak Mahaudomporn, Somkiet Nakasatien, Soontaree Himathongkam, Thep Salient features and outcomes of Charcot foot – An often-overlooked diabetic complication: A 17-year-experience at a diabetic center in Bangkok |
title | Salient features and outcomes of Charcot foot – An often-overlooked diabetic complication: A 17-year-experience at a diabetic center in Bangkok |
title_full | Salient features and outcomes of Charcot foot – An often-overlooked diabetic complication: A 17-year-experience at a diabetic center in Bangkok |
title_fullStr | Salient features and outcomes of Charcot foot – An often-overlooked diabetic complication: A 17-year-experience at a diabetic center in Bangkok |
title_full_unstemmed | Salient features and outcomes of Charcot foot – An often-overlooked diabetic complication: A 17-year-experience at a diabetic center in Bangkok |
title_short | Salient features and outcomes of Charcot foot – An often-overlooked diabetic complication: A 17-year-experience at a diabetic center in Bangkok |
title_sort | salient features and outcomes of charcot foot – an often-overlooked diabetic complication: a 17-year-experience at a diabetic center in bangkok |
topic | Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928004/ https://www.ncbi.nlm.nih.gov/pubmed/29725580 http://dx.doi.org/10.1016/j.jcte.2018.01.001 |
work_keys_str_mv | AT thewjitcharoenyotsapon salientfeaturesandoutcomesofcharcotfootanoftenoverlookeddiabeticcomplicationa17yearexperienceatadiabeticcenterinbangkok AT sripatpongjeeraphan salientfeaturesandoutcomesofcharcotfootanoftenoverlookeddiabeticcomplicationa17yearexperienceatadiabeticcenterinbangkok AT parksookwyn salientfeaturesandoutcomesofcharcotfootanoftenoverlookeddiabeticcomplicationa17yearexperienceatadiabeticcenterinbangkok AT krittiyawongsirinate salientfeaturesandoutcomesofcharcotfootanoftenoverlookeddiabeticcomplicationa17yearexperienceatadiabeticcenterinbangkok AT porramatikulsriurai salientfeaturesandoutcomesofcharcotfootanoftenoverlookeddiabeticcomplicationa17yearexperienceatadiabeticcenterinbangkok AT srikummoontaweesak salientfeaturesandoutcomesofcharcotfootanoftenoverlookeddiabeticcomplicationa17yearexperienceatadiabeticcenterinbangkok AT mahaudompornsomkiet salientfeaturesandoutcomesofcharcotfootanoftenoverlookeddiabeticcomplicationa17yearexperienceatadiabeticcenterinbangkok AT nakasatiensoontaree salientfeaturesandoutcomesofcharcotfootanoftenoverlookeddiabeticcomplicationa17yearexperienceatadiabeticcenterinbangkok AT himathongkamthep salientfeaturesandoutcomesofcharcotfootanoftenoverlookeddiabeticcomplicationa17yearexperienceatadiabeticcenterinbangkok |