Cargando…

Transcriptional landscape of Mycobacterium tuberculosis infection in macrophages

Mycobacterium tuberculosis (Mtb) infection reveals complex and dynamic host-pathogen interactions, leading to host protection or pathogenesis. Using a unique transcriptome technology (CAGE), we investigated the promoter-based transcriptional landscape of IFNγ (M1) or IL-4/IL-13 (M2) stimulated macro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Roy, Sugata, Schmeier, Sebastian, Kaczkowski, Bogumil, Arner, Erik, Alam, Tanvir, Ozturk, Mumin, Tamgue, Ousman, Parihar, Suraj P., Kawaji, Hideya, Itoh, Masayoshi, Lassmann, Timo, Carninci, Piero, Hayashizaki, Yoshihide, Forrest, Alistair R. R., Guler, Reto, Bajic, Vladimir B., Brombacher, Frank, Suzuki, Harukazu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928056/ https://www.ncbi.nlm.nih.gov/pubmed/29712924 http://dx.doi.org/10.1038/s41598-018-24509-6

Ejemplares similares

Redefining the transcriptional regulatory dynamics of classically and alternatively activated macrophages by deepCAGE transcriptomics
por: Roy, Sugata, et al.
Publicado: (2015)

IRNdb: the database of immunologically relevant non-coding RNAs
por: Denisenko, Elena, et al.
Publicado: (2016)

Differential Targeting of c-Maf, Bach-1, and Elmo-1 by microRNA-143 and microRNA-365 Promotes the Intracellular Growth of Mycobacterium tuberculosis in Alternatively IL-4/IL-13 Activated Macrophages
por: Tamgue, Ousman, et al.
Publicado: (2019)

IL-4Rα-Dependent Alternative Activation of Macrophages Is Not Decisive for Mycobacterium tuberculosis Pathology and Bacterial Burden in Mice
por: Guler, Reto, et al.
Publicado: (2015)

Lyl1-deficiency promotes inflammatory responses and increases mycobacterial burden in response to Mycobacterium tuberculosis infection in mice
por: Jones, Shelby-Sara, et al.
Publicado: (2022)

Conserved temporal ordering of promoter activation implicates common mechanisms governing the immediate early response across cell types and stimuli
por: Vacca, Annalaura, et al.
Publicado: (2018)

Mapping Mammalian Cell-type-specific Transcriptional Regulatory Networks Using KD-CAGE and ChIP-seq Data in the TC-YIK Cell Line
por: Lizio, Marina, et al.
Publicado: (2015)

Application of Gene Expression Trajectories Initiated from ErbB Receptor Activation Highlights the Dynamics of Divergent Promoter Usage
por: Carbajo, Daniel, et al.
Publicado: (2015)

Promoter-level expression clustering identifies time development of transcriptional regulatory cascades initiated by ErbB receptors in breast cancer cells
por: Mina, Marco, et al.
Publicado: (2015)

The frequent evolutionary birth and death of functional promoters in mouse and human
por: Young, Robert S., et al.
Publicado: (2015)

The FANTOM5 collection, a data series underpinning mammalian transcriptome atlases in diverse cell types
por: Kawaji, Hideya, et al.
Publicado: (2017)

Correction to: Relatively frequent switching of transcription start sites during cerebellar development
por: Zhang, Peter, et al.
Publicado: (2018)

Automated Workflow for Preparation of cDNA for Cap Analysis of Gene Expression on a Single Molecule Sequencer
por: Itoh, Masayoshi, et al.
Publicado: (2012)

Systematic analysis of transcription start sites in avian development
por: Lizio, Marina, et al.
Publicado: (2017)

Targeting Batf2 for infectious diseases and cancer
por: Guler, Reto, et al.
Publicado: (2015)

Transcriptional Dynamics Reveal Critical Roles for Non-coding RNAs in the Immediate-Early Response
por: Aitken, Stuart, et al.
Publicado: (2015)

Transcriptional Dynamics During Human Adipogenesis and Its Link to Adipose Morphology and Distribution
por: Ehrlund, Anna, et al.
Publicado: (2017)

Promoter Usage and Dynamics in Vascular Smooth Muscle Cells Exposed to Fibroblast Growth Factor-2 or Interleukin-1β
por: Alhendi, Ahmad M. N., et al.
Publicado: (2018)

Transcriptome Analysis Uncovers a Growth-Promoting Activity of Orosomucoid-1 on Hepatocytes
por: Qin, Xian-Yang, et al.
Publicado: (2017)

Transcriptome analysis of periodontitis-associated fibroblasts by CAGE sequencing identified DLX5 and RUNX2 long variant as novel regulators involved in periodontitis
por: Horie, Masafumi, et al.
Publicado: (2016)

Antisense Transcription in Loci Associated to Hereditary Neurodegenerative Diseases
por: Zucchelli, Silvia, et al.
Publicado: (2019)

RECLU: a pipeline to discover reproducible transcriptional start sites and their alternative regulation using capped analysis of gene expression (CAGE)
por: Ohmiya, Hiroko, et al.
Publicado: (2014)

Transcriptionally induced enhancers in the macrophage immune response to Mycobacterium tuberculosis infection
por: Denisenko, Elena, et al.
Publicado: (2019)

Analysis of the human monocyte-derived macrophage transcriptome and response to lipopolysaccharide provides new insights into genetic aetiology of inflammatory bowel disease
por: Baillie, J. Kenneth, et al.
Publicado: (2017)

Genome-wide profiling of transcribed enhancers during macrophage activation
por: Denisenko, Elena, et al.
Publicado: (2017)

Ceruloplasmin Is a Novel Adipokine Which Is Overexpressed in Adipose Tissue of Obese Subjects and in Obesity-Associated Cancer Cells
por: Arner, Erik, et al.
Publicado: (2014)

Simvastatin Enhances Protection against Listeria monocytogenes Infection in Mice by Counteracting Listeria-Induced Phagosomal Escape
por: Parihar, Suraj P., et al.
Publicado: (2013)

Targeting Molecular Inflammatory Pathways in Granuloma as Host-Directed Therapies for Tuberculosis
por: Guler, Reto, et al.
Publicado: (2021)

Identification of novel cerebellar developmental transcriptional regulators with motif activity analysis
por: Ha, Thomas J., et al.
Publicado: (2019)

Exploration of Small RNAs
por: Kawaji, Hideya, et al.
Publicado: (2008)

Evaluation of Berberine as an Adjunct to TB Treatment
por: Ozturk, Mumin, et al.
Publicado: (2021)

FANTOM4 EdgeExpressDB: an integrated database of promoters, genes, microRNAs, expression dynamics and regulatory interactions
por: Severin, Jessica, et al.
Publicado: (2009)

Monitoring transcription initiation activities in rat and dog
por: Lizio, Marina, et al.
Publicado: (2017)

The FANTOM web resource: from mammalian transcriptional landscape to its dynamic regulation
por: Kawaji, Hideya, et al.
Publicado: (2009)

Update of the FANTOM web resource: from mammalian transcriptional landscape to its dynamic regulation
por: Kawaji, Hideya, et al.
Publicado: (2011)

Functional annotation of the vlinc class of non-coding RNAs using systems biology approach
por: Laurent, Georges St., et al.
Publicado: (2016)

IL-4i1 Regulation of Immune Protection During Mycobacterium tuberculosis Infection
por: Hlaka, Lerato, et al.
Publicado: (2021)

Technical Advance: Transcription factor, promoter, and enhancer utilization in human myeloid cells
por: Joshi, Anagha, et al.
Publicado: (2015)

YY1 binding association with sex-biased transcription revealed through X-linked transcript levels and allelic binding analyses
por: Chen, Chih-yu, et al.
Publicado: (2016)

Restricted Presence of POU6F2 in Human Corneal Endothelial Cells Uncovered by Extension of the Promoter-level Expression Atlas
por: Yoshihara, Masahito, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_sl2bkapn02g9m99bvd0m6a8dgi