Essential Role of the a3 Isoform of V-ATPase in Secretory Lysosome Trafficking via Rab7 Recruitment

Secretory lysosomes are required for the specialised functions of various types of differentiated cells. In osteoclasts, the lysosomal proton pump V-ATPase (vacuolar-type ATPase) is targeted to the plasma membrane via secretory lysosomes and subsequently acidifies the extracellular compartment, prov...

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Detalles Bibliográficos
Autores principales: Matsumoto, Naomi, Sekiya, Mizuki, Tohyama, Koujiro, Ishiyama-Matsuura, Eri, Sun-Wada, Ge-Hong, Wada, Yoh, Futai, Masamitsu, Nakanishi-Matsui, Mayumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928161/
https://www.ncbi.nlm.nih.gov/pubmed/29712939
http://dx.doi.org/10.1038/s41598-018-24918-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928161/
https://www.ncbi.nlm.nih.gov/pubmed/29712939
http://dx.doi.org/10.1038/s41598-018-24918-7

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