SYK Inhibition Induces Apoptosis in Germinal Center-Like B Cells by Modulating the Antiapoptotic Protein Myeloid Cell Leukemia-1, Affecting B-Cell Activation and Antibody Production

B cells play a major role in the antibody-mediated rejection (AMR) of solid organ transplants, a major public health concern. The germinal center (GC) is involved in the generation of donor-specific antibody-producing plasma cells and memory B cells, which are often poorly controlled by current trea...

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Detalles Bibliográficos
Autores principales: Roders, Nathalie, Herr, Florence, Ambroise, Gorbatchev, Thaunat, Olivier, Portier, Alain, Vazquez, Aimé, Durrbach, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928208/
https://www.ncbi.nlm.nih.gov/pubmed/29740433
http://dx.doi.org/10.3389/fimmu.2018.00787

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