The senescence-associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1

The senescence-associated secretory phenotype (SASP) can be provoked by side effects of therapeutic agents, fueling advanced complications including cancer resistance. However, the intracellular signal network supporting initiation and development of the SASP driven by treatment-induced damage remai...

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Detalles Bibliográficos
Autores principales: Zhang, Boyi, Fu, Da, Xu, Qixia, Cong, Xianling, Wu, Chunyan, Zhong, Xiaoming, Ma, Yushui, Lv, Zhongwei, Chen, Fei, Han, Liu, Qian, Min, Chin, Y. Eugene, Lam, Eric W. -F., Chiao, Paul, Sun, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928226/
https://www.ncbi.nlm.nih.gov/pubmed/29712904
http://dx.doi.org/10.1038/s41467-018-04010-4

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