A functional genomic screen in vivo identifies CEACAM5 as a clinically relevant driver of breast cancer metastasis

Tumor cells disseminate early in tumor development making metastasis-prevention strategies difficult. Identifying proteins that promote the outgrowth of disseminated tumor cells may provide opportunities for novel therapeutic strategies. Despite multiple studies demonstrating that the mesenchymal-to...

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Detalles Bibliográficos
Autores principales: Powell, Emily, Shao, Jiansu, Picon, Hector M., Bristow, Christopher, Ge, Zhongqi, Peoples, Michael, Robinson, Frederick, Jeter-Jones, Sabrina L., Schlosberg, Christopher, Grzeskowiak, Caitlin L., Yang, Fei, Wu, Yun, Wistuba, Ignacio, Moulder, Stacy L., Symmans, William F., Scott, Kenneth L., Edwards, John R., Liang, Han, Heffernan, Timothy P., Piwnica-Worms, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928229/
https://www.ncbi.nlm.nih.gov/pubmed/29736411
http://dx.doi.org/10.1038/s41523-018-0062-x

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