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Assessment of Neutron Contamination Originating from the Presence of Wedge and Block in Photon Beam Radiotherapy

BACKGROUND: One of the main causes of induction of secondary cancer in radiation therapy is neutron contamination received by patients during treatment. Objective: In the present study the impact of wedge and block on neutron contamination production is investigated. The evaluations are conducted fo...

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Autores principales: Bahreyni Toossi, M.T., Khajetash, B., Ghorbani, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Biomedical Physics and Engineering 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928309/
https://www.ncbi.nlm.nih.gov/pubmed/29732336
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author Bahreyni Toossi, M.T.
Khajetash, B.
Ghorbani, M.
author_facet Bahreyni Toossi, M.T.
Khajetash, B.
Ghorbani, M.
author_sort Bahreyni Toossi, M.T.
collection PubMed
description BACKGROUND: One of the main causes of induction of secondary cancer in radiation therapy is neutron contamination received by patients during treatment. Objective: In the present study the impact of wedge and block on neutron contamination production is investigated. The evaluations are conducted for a 15 MV Siemens Primus linear accelerator. METHODS: Simulations were performed using MCNPX Monte Carlo code. 30˚, 45˚ and 60˚ wedges and a cerrobend block with dimensions of 1.5 × 1.5 × 7 cm(3) were simulated. The investigation were performed in the 10 × 10 cm(2) field size at source to surface distance of 100 cm for depth of 0.5, 2, 3 and 4 cm in a water phantom. Neutron dose was calculated using F4 tally with flux to dose conversion factors and F6 tally. RESULTS: Results showed that the presence of wedge increases the neutron contamination when the wedge factor was considered. In addition, 45˚ wedge produced the most amount of neutron contamination. If the block is in the center of the field, the cerrobend block caused less neutron contamination than the open field due to absorption of neutrons and photon attenuation. The results showed that neutron contamination is less in steeper depths. The results for two tallies showed practically equivalent results. CONCLUSION: Wedge causes neutron contamination hence should be considered in therapeutic protocols in which wedge is used. In terms of clinical aspects, the results of this study show that superficial tissues such as skin will tolerate more neutron contamination than the deep tissues.
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spelling pubmed-59283092018-05-04 Assessment of Neutron Contamination Originating from the Presence of Wedge and Block in Photon Beam Radiotherapy Bahreyni Toossi, M.T. Khajetash, B. Ghorbani, M. J Biomed Phys Eng Original Article BACKGROUND: One of the main causes of induction of secondary cancer in radiation therapy is neutron contamination received by patients during treatment. Objective: In the present study the impact of wedge and block on neutron contamination production is investigated. The evaluations are conducted for a 15 MV Siemens Primus linear accelerator. METHODS: Simulations were performed using MCNPX Monte Carlo code. 30˚, 45˚ and 60˚ wedges and a cerrobend block with dimensions of 1.5 × 1.5 × 7 cm(3) were simulated. The investigation were performed in the 10 × 10 cm(2) field size at source to surface distance of 100 cm for depth of 0.5, 2, 3 and 4 cm in a water phantom. Neutron dose was calculated using F4 tally with flux to dose conversion factors and F6 tally. RESULTS: Results showed that the presence of wedge increases the neutron contamination when the wedge factor was considered. In addition, 45˚ wedge produced the most amount of neutron contamination. If the block is in the center of the field, the cerrobend block caused less neutron contamination than the open field due to absorption of neutrons and photon attenuation. The results showed that neutron contamination is less in steeper depths. The results for two tallies showed practically equivalent results. CONCLUSION: Wedge causes neutron contamination hence should be considered in therapeutic protocols in which wedge is used. In terms of clinical aspects, the results of this study show that superficial tissues such as skin will tolerate more neutron contamination than the deep tissues. Journal of Biomedical Physics and Engineering 2018-03-01 /pmc/articles/PMC5928309/ /pubmed/29732336 Text en Copyright: © Journal of Biomedical Physics and Engineering http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Bahreyni Toossi, M.T.
Khajetash, B.
Ghorbani, M.
Assessment of Neutron Contamination Originating from the Presence of Wedge and Block in Photon Beam Radiotherapy
title Assessment of Neutron Contamination Originating from the Presence of Wedge and Block in Photon Beam Radiotherapy
title_full Assessment of Neutron Contamination Originating from the Presence of Wedge and Block in Photon Beam Radiotherapy
title_fullStr Assessment of Neutron Contamination Originating from the Presence of Wedge and Block in Photon Beam Radiotherapy
title_full_unstemmed Assessment of Neutron Contamination Originating from the Presence of Wedge and Block in Photon Beam Radiotherapy
title_short Assessment of Neutron Contamination Originating from the Presence of Wedge and Block in Photon Beam Radiotherapy
title_sort assessment of neutron contamination originating from the presence of wedge and block in photon beam radiotherapy
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928309/
https://www.ncbi.nlm.nih.gov/pubmed/29732336
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