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Monte Carlo Simulation of Electron Beams produced by LIAC Intraoperative Radiation Therapy Accelerator

BACKGROUND: One of the main problems of dedicated IORT accelerators is to determine dosimetric characteristics of the electron beams. Monte Carlo simulation of IORT accelerator head and produced beam will be useful to improve the accuracy of beam dosimetry. MATERIALS AND METHODS: Liac accelerator he...

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Detalles Bibliográficos
Autores principales: Robatjazi, M., Tanha, K., Mahdavi, S.R., Baghani, H.R., Mirzaei, H.R., Mousavi, M., Nafissi, N., Akbari, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Biomedical Physics and Engineering 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928310/
https://www.ncbi.nlm.nih.gov/pubmed/29732339
Descripción
Sumario:BACKGROUND: One of the main problems of dedicated IORT accelerators is to determine dosimetric characteristics of the electron beams. Monte Carlo simulation of IORT accelerator head and produced beam will be useful to improve the accuracy of beam dosimetry. MATERIALS AND METHODS: Liac accelerator head was modeled using the BEAMnrcMonte Carlo simulation system. Phase-space files were generated at the bottom of the applicators. These phase-space files were used as an input source in DOSXYZnrc and BEAMDP codes for dose calculation and analysis of the characteristic of the electron beams in all applicators and energies. RESULTS: The results of Monte Carlo calculations are in very close agreement with the measurements. There is a decrease in the peak of the initial spectrum when electrons come from the end of accelerator wave guide to the end of applicator. By decreasing the applicator diameter, the mean energy of electron beam decreased. Using applicators and increasing their size, X-ray contamination will increase. The percentage of X-ray contamination increases by applicator diameter. This is related to the increase of the mean energy of electron beams. CONCLUSION: Application of PMMA collimator leads to, although well below accepted level, the production of bremsstrahlung. The results of this study showed that special design of LIAC head accompanying by PMMA collimator system cause to produce an electron beam with an individual dosimetric characteristic making it a useful tool for intraoperative radiotherapy purposes.