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Revisited analysis of a SHIVA01 trial cohort using functional mutational analyses successfully predicted treatment outcome

It still remains to be demonstrated that using molecular profiling to guide therapy improves patient outcome in oncology. Classification of somatic variants is not straightforward, rendering treatment decisions based on variants with unknown significance (VUS) hard to implement. The oncogenic activi...

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Detalles Bibliográficos
Autores principales:	Kamal, Maud, Tarcic, Gabi, Dureau, Sylvain, Edelheit, Oded, Barbash, Zohar, Lecerf, Charlotte, Morel, Claire, Miron, Benjamin, Callens, Celine, Servant, Nicolas, Bieche, Ivan, Vidne, Michael, Le Tourneau, Christophe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928387/ https://www.ncbi.nlm.nih.gov/pubmed/29464843 http://dx.doi.org/10.1002/1878-0261.12180

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