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Comparative whole genome DNA methylation profiling of cattle sperm and somatic tissues reveals striking hypomethylated patterns in sperm
BACKGROUND: Although sperm DNA methylation has been studied in humans and other species, its status in cattle is largely unknown. RESULTS: Using whole-genome bisulfite sequencing (WGBS), we profiled the DNA methylome of cattle sperm through comparison with three somatic tissues (mammary gland, brain...
Autores principales: | Zhou, Yang, Connor, Erin E, Bickhart, Derek M, Li, Congjun, Baldwin, Ransom L, Schroeder, Steven G, Rosen, Benjamin D, Yang, Liguo, Van Tassell, Curtis P, Liu, George E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928411/ https://www.ncbi.nlm.nih.gov/pubmed/29635292 http://dx.doi.org/10.1093/gigascience/giy039 |
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