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Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion

Proteases of the malaria parasite Plasmodium falciparum have long been investigated as drug targets. The P. falciparum genome encodes 10 aspartic proteases called plasmepsins, which are involved in diverse cellular processes. Most have been studied extensively but the functions of plasmepsins IX and...

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Detalles Bibliográficos
Autores principales:	Nasamu, Armiyaw S., Glushakova, Svetlana, Russo, Ilaria, Vaupel, Barbara, Oksman, Anna, Kim, Arthur S., Fremont, Daved H., Tolia, Niraj, Beck, Josh R., Meyers, Marvin J., Niles, Jacquin C., Zimmerberg, Joshua, Goldberg, Daniel E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2017
Materias:	Malaria
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928414/ https://www.ncbi.nlm.nih.gov/pubmed/29074774 http://dx.doi.org/10.1126/science.aan1478

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