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Design, Synthesis, and Biological Evaluations of Asymmetric Bow-Tie PAMAM Dendrimer-Based Conjugates for Tumor-Targeted Drug Delivery

[Image: see text] A unique asymmetric bow-tie poly(amidoamine) (PAMAM) dendrimer (ABTD) scaffold was designed and developed as a well-defined macromolecular carrier for tumor-targeted drug delivery. The ABTD scaffold in this study consists of a G3-half-dendron (G3-HD) unit and a G1-half-dendron (G1-...

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Detalles Bibliográficos
Autores principales: Wang, Tao, Zhang, Yaozhong, Wei, Longfei, Teng, Yuhan G., Honda, Tadashi, Ojima, Iwao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928494/
https://www.ncbi.nlm.nih.gov/pubmed/29732446
http://dx.doi.org/10.1021/acsomega.8b00409