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Penehyclidine hydrochloride inhibits TLR4 signaling and inflammation, and attenuates blunt chest trauma and hemorrhagic shock-induced acute lung injury in rats

Blunt chest trauma with hemorrhagic shock (THS) frequently induces pulmonary inflammation that leads to acute lung injury (ALI). Penehyclidine hydrochloride (PHC) possesses anti-inflammatory properties that may attenuate the systemic inflammatory response. The present study aimed to evaluate the mol...

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Detalles Bibliográficos
Autores principales: Wu, Xiao-Jing, Liu, Hui-Min, Song, Xue-Min, Zhao, Bo, Leng, Yan, Wang, E-You, Zhan, Li-Ying, Meng, Qing-Tao, Xia, Zhong-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928610/
https://www.ncbi.nlm.nih.gov/pubmed/29488614
http://dx.doi.org/10.3892/mmr.2018.8644