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Penehyclidine hydrochloride inhibits TLR4 signaling and inflammation, and attenuates blunt chest trauma and hemorrhagic shock-induced acute lung injury in rats
Blunt chest trauma with hemorrhagic shock (THS) frequently induces pulmonary inflammation that leads to acute lung injury (ALI). Penehyclidine hydrochloride (PHC) possesses anti-inflammatory properties that may attenuate the systemic inflammatory response. The present study aimed to evaluate the mol...
Autores principales: | Wu, Xiao-Jing, Liu, Hui-Min, Song, Xue-Min, Zhao, Bo, Leng, Yan, Wang, E-You, Zhan, Li-Ying, Meng, Qing-Tao, Xia, Zhong-Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928610/ https://www.ncbi.nlm.nih.gov/pubmed/29488614 http://dx.doi.org/10.3892/mmr.2018.8644 |
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