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Atorvastatin prevents glomerular extracellular matrix formation by interfering with the PKC signaling pathway

Platelet-activating factor (PAF) promotes glomerular extracellular matrix (ECM) deposition, primarily through activation of the protein kinase C (PKC) pathway. The present study was designed to investigate whether atorvastatin, which mediates a protective effect against glomerular ECM deposition and...

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Detalles Bibliográficos
Autores principales: Xiao, Yan-Hua, He, Xiao-Yun, Han, Qing, Yang, Fan, Zhou, Su-Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928626/
https://www.ncbi.nlm.nih.gov/pubmed/29532876
http://dx.doi.org/10.3892/mmr.2018.8724