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Companion Diagnostic (64)Cu-Liposome Positron Emission Tomography Enables Characterization of Drug Delivery to Tumors and Predicts Response to Cancer Nanomedicines

Deposition of liposomal drugs into solid tumors is a potentially rate-limiting step for drug delivery and has substantial variability that may influence probability of response. Tumor deposition is a shared mechanism for liposomal therapeutics such that a single companion diagnostic agent may have u...

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Detalles Bibliográficos
Autores principales: Lee, Helen, Gaddy, Daniel, Ventura, Manuela, Bernards, Nicholas, de Souza, Raquel, Kirpotin, Dmitri, Wickham, Thomas, Fitzgerald, Jonathan, Zheng, Jinzi, Hendriks, Bart S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928891/
https://www.ncbi.nlm.nih.gov/pubmed/29721081
http://dx.doi.org/10.7150/thno.21670