Cargando…
Targeting CPT1A-mediated fatty acid oxidation sensitizes nasopharyngeal carcinoma to radiation therapy
Nasopharyngeal carcinoma (NPC) has a particularly high prevalence in southern China, southeastern Asia and northern Africa. Radiation resistance remains a serious obstacle to successful treatment in NPC. This study aimed to explore the metabolic feature of radiation-resistant NPC cells and identify...
Autores principales: | Tan, Zheqiong, Xiao, Lanbo, Tang, Min, Bai, Fang, Li, Jiangjiang, Li, Liling, Shi, Feng, Li, Namei, Li, Yueshuo, Du, Qianqian, Lu, Jingchen, Weng, Xinxian, Yi, Wei, Zhang, Hanwen, Fan, Jia, Zhou, Jian, Gao, Qiang, Onuchic, José N., Bode, Ann M., Luo, Xiangjian, Cao, Ya |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928893/ https://www.ncbi.nlm.nih.gov/pubmed/29721083 http://dx.doi.org/10.7150/thno.21451 |
Ejemplares similares
-
PGC1α/CEBPB/CPT1A axis promotes radiation resistance of nasopharyngeal carcinoma through activating fatty acid oxidation
por: Du, Qianqian, et al.
Publicado: (2019) -
CPT1A-mediated fatty acid oxidation promotes cell proliferation via nucleoside metabolism in nasopharyngeal carcinoma
por: Tang, Min, et al.
Publicado: (2022) -
Wild-type IDH2 promotes the Warburg effect and tumor growth through HIF1α in lung cancer
por: Li, Jiangjiang, et al.
Publicado: (2018) -
Emerging roles of lipid metabolism in cancer metastasis
por: Luo, Xiangjian, et al.
Publicado: (2017) -
Grifolin inhibits tumor cells adhesion and migration via suppressing interplay between PGC1α and Fra-1/LSF-MMP2/CD44 axes
por: Luo, Xiangjian, et al.
Publicado: (2016)