MicroRNA-378 suppresses myocardial fibrosis through a paracrine mechanism at the early stage of cardiac hypertrophy following mechanical stress.

Rationale: Excessive myocardial fibrosis is the main pathological process in the development of cardiac remodeling and heart failure; therefore, it is important to prevent excessive myocardial fibrosis. We determined that microRNA-378 (miR-378) is cardiac-enriched and highly repressed during cardiac...

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Detalles Bibliográficos
Autores principales: Yuan, Jie, Liu, Haibo, Gao, Wei, Zhang, Li, Ye, Yong, Yuan, Lingyan, Ding, Zhiwen, Wu, Jian, Kang, Le, Zhang, Xiaoyi, Wang, Xiaoyan, Zhang, Guoping, Gong, Hui, Sun, Aijun, Yang, Xiangdong, Chen, Ruizhen, Cui, Zhaoqiang, Ge, Junbo, Zou, Yunzeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928909/
https://www.ncbi.nlm.nih.gov/pubmed/29721099
http://dx.doi.org/10.7150/thno.22878

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