Cargando…
Establishing sheep as an experimental species to validate ultrasound-mediated blood-brain barrier opening for potential therapeutic interventions
Rationale: Treating diseases of the brain such as Alzheimer's disease (AD) is challenging as the blood-brain barrier (BBB) effectively restricts access of a large number of potentially useful drugs. A potential solution to this problem is presented by therapeutic ultrasound, a novel treatment m...
Autores principales: | Pelekanos, Matthew, Leinenga, Gerhard, Odabaee, Mostafa, Odabaee, Maryam, Saifzadeh, Siamak, Steck, Roland, Götz, Jürgen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928910/ https://www.ncbi.nlm.nih.gov/pubmed/29721100 http://dx.doi.org/10.7150/thno.22852 |
Ejemplares similares
-
Ultrasound-mediated blood-brain barrier opening enhances delivery of therapeutically relevant formats of a tau-specific antibody
por: Janowicz, Phillip W., et al.
Publicado: (2019) -
Safety and Efficacy of Scanning Ultrasound Treatment of Aged APP23 Mice
por: Leinenga, Gerhard, et al.
Publicado: (2018) -
Repeated ultrasound treatment of tau transgenic mice clears neuronal tau by autophagy and improves behavioral functions
por: Pandit, Rucha, et al.
Publicado: (2019) -
Claudin-5 binder enhances focused ultrasound-mediated opening in an in vitro blood-brain barrier model
por: Chen, Liyu, et al.
Publicado: (2022) -
A comparative study of the effects of Aducanumab and scanning ultrasound on amyloid plaques and behavior in the APP23 mouse model of Alzheimer disease
por: Leinenga, Gerhard, et al.
Publicado: (2021)