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Secretory Clusterin Mediates Oxaliplatin Resistance via the Gadd45a/PI3K/Akt Signaling Pathway in Hepatocellular Carcinoma

Purpose: Systemic therapy has often been used for patients with advanced hepatocellular carcinoma (HCC). However, due to drug resistance, the use of cytotoxic chemotherapy in the treatment of patients with advanced HCC has typically demonstrated low response rates. Secretory clusterin (sCLU) is expr...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Zou, Fang, Zhong, Jingtao, Yue, Longtao, Wang, Fuhai, Wei, Honglong, Yang, Guangsheng, Jin, Tao, Dong, Xiaofeng, Li, Jie, Xiu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929085/
https://www.ncbi.nlm.nih.gov/pubmed/29721050
http://dx.doi.org/10.7150/jca.23849