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Impact of Sickle Cell Trait and Naturally Acquired Immunity on Uncomplicated Malaria after Controlled Human Malaria Infection in Adults in Gabon

Controlled human malaria infection (CHMI) by direct venous inoculation (DVI) with 3,200 cryopreserved Plasmodium falciparum sporozoites (PfSPZ) consistently leads to parasitemia and malaria symptoms in malaria-naive adults. We used CHMI by DVI to investigate infection rates, parasite kinetics, and m...

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Detalles Bibliográficos
Autores principales:	Lell, Bertrand, Mordmüller, Benjamin, Dejon Agobe, Jean-Claude, Honkpehedji, Josiane, Zinsou, Jeannot, Mengue, Juliana Boex, Loembe, Marguerite Massinga, Adegnika, Ayola Akim, Held, Jana, Lalremruata, Albert, Nguyen, The Trong, Esen, Meral, KC, Natasha, Ruben, Adam J., Chakravarty, Sumana, Lee Sim, B. Kim, Billingsley, Peter F., James, Eric R., Richie, Thomas L., Hoffman, Stephen L., Kremsner, Peter G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society of Tropical Medicine and Hygiene 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929186/ https://www.ncbi.nlm.nih.gov/pubmed/29260650 http://dx.doi.org/10.4269/ajtmh.17-0343

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