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Main implications related to the switch to BRCA1/2 tumor testing in ovarian cancer patients: a proposal of a consensus

BACKGROUND: Since the approval of the first poly (adenosine diphosphate [ADP]) ribose polymerase inhibitor (PARPi; olaparib [Lynparza™]) for platinum-sensitive relapsed high grade ovarian cancer, with either germline or somatic BRCA1/2 deleterious variants, the strategies for BRCA1/2 are dynamically...

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Detalles Bibliográficos
Autores principales:	Capoluongo, Ettore, Scambia, Giovanni, Nabholtz, Jean-Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929401/ https://www.ncbi.nlm.nih.gov/pubmed/29731958 http://dx.doi.org/10.18632/oncotarget.24728

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