Deletion of plasma Phospholipid Transfer Protein (PLTP) increases microglial phagocytosis and reduces cerebral amyloid-β deposition in the J20 mouse model of Alzheimer's disease

Plasma phospholipid transfer protein (PLTP) binds and transfers a number of amphipathic compounds, including phospholipids, cholesterol, diacylglycerides, tocopherols and lipopolysaccharides. PLTP functions are relevant for many pathophysiological alterations involved in neurodegenerative disorders...

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Detalles Bibliográficos
Autores principales: Mansuy, Marine, Baille, Stella, Canet, Geoffrey, Borie, Amélie, Cohen-Solal, Catherine, Vignes, Michel, Perrier, Véronique, Chevallier, Nathalie, Le Guern, Naig, Deckert, Valérie, Lagrost, Laurent, Givalois, Laurent, Desrumaux, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929418/
https://www.ncbi.nlm.nih.gov/pubmed/29731975
http://dx.doi.org/10.18632/oncotarget.24802

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