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Bacterial versus human thymidylate synthase: Kinetics and functionality

Thymidylate Synthase (TSase) is a highly conserved enzyme that catalyzes the production of the DNA building block thymidylate. Structurally, functionally and mechanistically, bacterial and mammalian TSases share remarkable similarities. Because of this closeness, bacterial enzymes have long been use...

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Detalles Bibliográficos
Autores principales:	Islam, Zahidul, Gurevic, Ilya, Strutzenberg, Timothy S., Ghosh, Ananda K., Iqbal, Tasnia, Kohen, Amnon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929524/ https://www.ncbi.nlm.nih.gov/pubmed/29715278 http://dx.doi.org/10.1371/journal.pone.0196506

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