Exome array analysis of adverse reactions to fluoropyrimidine-based therapy for gastrointestinal cancer

Fluoropyrimidines, including 5-fluororacil (5FU) and its pro-drug Capecitabine, are the common treatment for colorectal, breast, neck and head cancers—either as monotherapy or in combination therapy. Adverse reactions (ADRs) to the treatment are common and often result in treatment discontinuation o...

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Detalles Bibliográficos
Autores principales: Traylor, Matthew, Walker, Jemma L., Corrigan, Adele A., Hernandez, Monica A., Newhouse, Stephen J., Folarin, Amos A., Patel, Hamel, Ross, Paul J., Sanderson, Jeremy D., Spicer, James, Prescott, Natalie J., Mathew, Christopher G., Marinaki, Anthony M., Lewis, Cathryn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929530/
https://www.ncbi.nlm.nih.gov/pubmed/29715290
http://dx.doi.org/10.1371/journal.pone.0188911

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