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A PKC-MARCKS-PI3K regulatory module links Ca(2+) and PIP(3) signals at the leading edge of polarized macrophages

The leukocyte chemosensory pathway detects attractant gradients and directs cell migration to sites of inflammation, infection, tissue damage, and carcinogenesis. Previous studies have revealed that local Ca(2+) and PIP(3) signals at the leading edge of polarized leukocytes play central roles in pos...

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Detalles Bibliográficos
Autores principales: Ziemba, Brian P., Falke, Joseph J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929533/
https://www.ncbi.nlm.nih.gov/pubmed/29715315
http://dx.doi.org/10.1371/journal.pone.0196678