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A PKC-MARCKS-PI3K regulatory module links Ca(2+) and PIP(3) signals at the leading edge of polarized macrophages
The leukocyte chemosensory pathway detects attractant gradients and directs cell migration to sites of inflammation, infection, tissue damage, and carcinogenesis. Previous studies have revealed that local Ca(2+) and PIP(3) signals at the leading edge of polarized leukocytes play central roles in pos...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929533/ https://www.ncbi.nlm.nih.gov/pubmed/29715315 http://dx.doi.org/10.1371/journal.pone.0196678 |