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TMSOTf assisted synthesis of 2’-deoxy-2’-[(18)F]fluoro-β-D-arabinofuranosylcytosine ([(18)F]FAC)
[(18)F]FAC (2’-deoxy-2’-[(18)F]fluoro-β-D-arabinofuranosylcytosine, 1) is a versatile probe for imaging deoxycytidine kinase (dCK) expression levels in vivo. dCK is responsible for phosphorylation of deoxycytidine (dC, 2) and other nucleoside analogs, plays a key role in immune activation and has de...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929562/ https://www.ncbi.nlm.nih.gov/pubmed/29715301 http://dx.doi.org/10.1371/journal.pone.0196784 |