Type I interferon signaling attenuates regulatory T cell function in viral infection and in the tumor microenvironment

Regulatory T cells (Tregs) play a cardinal role in the immune system by suppressing detrimental autoimmune responses, but their role in acute, chronic infectious diseases and tumor microenvironment remains unclear. We recently demonstrated that IFN-α/β receptor (IFNAR) signaling promotes Treg functi...

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Detalles Bibliográficos
Autores principales: Gangaplara, Arunakumar, Martens, Craig, Dahlstrom, Eric, Metidji, Amina, Gokhale, Ameya S., Glass, Deborah D., Lopez-Ocasio, Maria, Baur, Rachel, Kanakabandi, Kishore, Porcella, Stephen F., Shevach, Ethan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929570/
https://www.ncbi.nlm.nih.gov/pubmed/29672594
http://dx.doi.org/10.1371/journal.ppat.1006985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929570/
https://www.ncbi.nlm.nih.gov/pubmed/29672594
http://dx.doi.org/10.1371/journal.ppat.1006985

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