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Membrane Mucin Muc4 Promotes Blood Cell Association with Tumor Cells and Mediates Efficient Metastasis in a Mouse Model of Breast Cancer

Mucin-4 (Muc4) is a large cell surface glycoprotein implicated in the protection and lubrication of epithelial structures. Previous studies suggest that aberrantly expressed Muc4 can influence the adhesiveness, proliferation, viability and invasiveness of cultured tumor cells, as well as the growth...

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Detalles Bibliográficos
Autores principales: Rowson-Hodel, A.R., Wald, J.H., Hatakeyama, J., O’Neal, W.K., Stonebraker, J.R., VanderVorst, K., Saldana, M.J., Borowsky, A.D., Sweeney, C., Carraway, K.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930013/
https://www.ncbi.nlm.nih.gov/pubmed/28892049
http://dx.doi.org/10.1038/onc.2017.327