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SUN2 Modulates HIV-1 Infection and Latency through Association with Lamin A/C To Maintain the Repressive Chromatin

The postintegrational latency of HIV-1 is characterized by reversible silencing of long terminal repeat (LTR)-driven transcription of the HIV genome. It is known that the formation of repressive chromatin at the 5′-LTR of HIV-1 proviral DNA impedes viral transcription by blocking the recruitment of...

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Detalles Bibliográficos
Autores principales: Sun, Wei-Wei, Jiao, Shi, Sun, Li, Zhou, Zhaocai, Jin, Xia, Wang, Jian-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930302/
https://www.ncbi.nlm.nih.gov/pubmed/29717016
http://dx.doi.org/10.1128/mBio.02408-17

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