Nanog interaction with the androgen receptor signaling axis induce ovarian cancer stem cell regulation: studies based on the CRISPR/Cas9 system

BACKGROUND: Ovarian cancer stem cells (OCSCs) contribute to the poor prognosis of ovarian cancer. Involvement of the androgen receptor (AR) in the malignant behaviors of other tumors has been reported. However, whether AR associates with Nanog (a stem cell marker) and participates in OCSC functions...

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Detalles Bibliográficos
Autores principales: Ling, Kaijian, Jiang, Lupin, Liang, Shi, Kwong, Joseph, Yang, Leiyan, Li, Yudi, PingYin, Deng, Qingchun, Liang, Zhiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930492/
https://www.ncbi.nlm.nih.gov/pubmed/29716628
http://dx.doi.org/10.1186/s13048-018-0403-2

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