Human platelet lysate in mesenchymal stromal cell expansion according to a GMP grade protocol: a cell factory experience

BACKGROUND: The use of platelet lysate (PL) for the ex-vivo expansion of mesenchymal stromal/stem cells (MSCs) was initially proposed by Doucet et al. in 2005, as an alternative to animal serum. Moreover, regulatory authorities discourage the use of fetal bovine serum (FBS) or other animal derivativ...

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Detalles Bibliográficos
Autores principales: Becherucci, Valentina, Piccini, Luisa, Casamassima, Serena, Bisin, Silvia, Gori, Valentina, Gentile, Francesca, Ceccantini, Riccardo, De Rienzo, Elena, Bindi, Barbara, Pavan, Paola, Cunial, Vanessa, Allegro, Elisa, Ermini, Stefano, Brugnolo, Francesca, Astori, Giuseppe, Bambi, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930506/
https://www.ncbi.nlm.nih.gov/pubmed/29720245
http://dx.doi.org/10.1186/s13287-018-0863-8

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