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Reconstruction of a replication-competent ancestral murine endogenous retrovirus-L

BACKGROUND: About 10% of the mouse genome is composed of endogenous retroviruses (ERVs) that represent a molecular fossil record of past retroviral infections. One such retrovirus, murine ERV-L (MuERV-L) is an env-deficient ERV that has undergone episodic proliferation, with the most recent amplific...

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Detalles Bibliográficos
Autores principales: Blanco-Melo, Daniel, Gifford, Robert J., Bieniasz, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930517/
https://www.ncbi.nlm.nih.gov/pubmed/29716624
http://dx.doi.org/10.1186/s12977-018-0416-3

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