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Indolent Systemic Mastocytosis Manifesting as Protracted Anaphylactic Shock

Systemic mastocytosis is a rare disease due to abnormal proliferation of mast cells (MCs). A case of indolent systemic mastocytosis is presented here. After anesthetic induction for elective thyroid swelling with propofol and atracurium followed by endotracheal intubation, a 57-year-old female patie...

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Detalles Bibliográficos
Autores principales: Chatterjee, Manidipam, Sengupta, Saikat, Chakravarty, Chandrashish, Ramasubban, Suresh, Bhartia, Shilpa, Khan, Sujoy, Agarwal, Vikash Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930539/
https://www.ncbi.nlm.nih.gov/pubmed/29743774
http://dx.doi.org/10.4103/ijccm.IJCCM_497_17
Descripción
Sumario:Systemic mastocytosis is a rare disease due to abnormal proliferation of mast cells (MCs). A case of indolent systemic mastocytosis is presented here. After anesthetic induction for elective thyroid swelling with propofol and atracurium followed by endotracheal intubation, a 57-year-old female patient developed acute hypotension, sinus tachycardia, red rashes, increased airway pressure along with difficult ventilation, and desaturation. She developed multiorgan failure subsequently. MC tryptase level was persistently high. Bone marrow study revealed mastocytosis. She required antihistaminic, steroid, and organ support. With treatment, organ functions recovered gradually. Atracurium precipitated anaphylactic shock causing severe morbidity in this patient.