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Indolent Systemic Mastocytosis Manifesting as Protracted Anaphylactic Shock
Systemic mastocytosis is a rare disease due to abnormal proliferation of mast cells (MCs). A case of indolent systemic mastocytosis is presented here. After anesthetic induction for elective thyroid swelling with propofol and atracurium followed by endotracheal intubation, a 57-year-old female patie...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930539/ https://www.ncbi.nlm.nih.gov/pubmed/29743774 http://dx.doi.org/10.4103/ijccm.IJCCM_497_17 |
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author | Chatterjee, Manidipam Sengupta, Saikat Chakravarty, Chandrashish Ramasubban, Suresh Bhartia, Shilpa Khan, Sujoy Agarwal, Vikash Kumar |
author_facet | Chatterjee, Manidipam Sengupta, Saikat Chakravarty, Chandrashish Ramasubban, Suresh Bhartia, Shilpa Khan, Sujoy Agarwal, Vikash Kumar |
author_sort | Chatterjee, Manidipam |
collection | PubMed |
description | Systemic mastocytosis is a rare disease due to abnormal proliferation of mast cells (MCs). A case of indolent systemic mastocytosis is presented here. After anesthetic induction for elective thyroid swelling with propofol and atracurium followed by endotracheal intubation, a 57-year-old female patient developed acute hypotension, sinus tachycardia, red rashes, increased airway pressure along with difficult ventilation, and desaturation. She developed multiorgan failure subsequently. MC tryptase level was persistently high. Bone marrow study revealed mastocytosis. She required antihistaminic, steroid, and organ support. With treatment, organ functions recovered gradually. Atracurium precipitated anaphylactic shock causing severe morbidity in this patient. |
format | Online Article Text |
id | pubmed-5930539 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-59305392018-05-09 Indolent Systemic Mastocytosis Manifesting as Protracted Anaphylactic Shock Chatterjee, Manidipam Sengupta, Saikat Chakravarty, Chandrashish Ramasubban, Suresh Bhartia, Shilpa Khan, Sujoy Agarwal, Vikash Kumar Indian J Crit Care Med Case Report Systemic mastocytosis is a rare disease due to abnormal proliferation of mast cells (MCs). A case of indolent systemic mastocytosis is presented here. After anesthetic induction for elective thyroid swelling with propofol and atracurium followed by endotracheal intubation, a 57-year-old female patient developed acute hypotension, sinus tachycardia, red rashes, increased airway pressure along with difficult ventilation, and desaturation. She developed multiorgan failure subsequently. MC tryptase level was persistently high. Bone marrow study revealed mastocytosis. She required antihistaminic, steroid, and organ support. With treatment, organ functions recovered gradually. Atracurium precipitated anaphylactic shock causing severe morbidity in this patient. Medknow Publications & Media Pvt Ltd 2018-04 /pmc/articles/PMC5930539/ /pubmed/29743774 http://dx.doi.org/10.4103/ijccm.IJCCM_497_17 Text en Copyright: © 2018 Indian Journal of Critical Care Medicine http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Chatterjee, Manidipam Sengupta, Saikat Chakravarty, Chandrashish Ramasubban, Suresh Bhartia, Shilpa Khan, Sujoy Agarwal, Vikash Kumar Indolent Systemic Mastocytosis Manifesting as Protracted Anaphylactic Shock |
title | Indolent Systemic Mastocytosis Manifesting as Protracted Anaphylactic Shock |
title_full | Indolent Systemic Mastocytosis Manifesting as Protracted Anaphylactic Shock |
title_fullStr | Indolent Systemic Mastocytosis Manifesting as Protracted Anaphylactic Shock |
title_full_unstemmed | Indolent Systemic Mastocytosis Manifesting as Protracted Anaphylactic Shock |
title_short | Indolent Systemic Mastocytosis Manifesting as Protracted Anaphylactic Shock |
title_sort | indolent systemic mastocytosis manifesting as protracted anaphylactic shock |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930539/ https://www.ncbi.nlm.nih.gov/pubmed/29743774 http://dx.doi.org/10.4103/ijccm.IJCCM_497_17 |
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