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6% Hydroxyethyl starch (HES 130/0.4) diminishes glycocalyx degradation and decreases vascular permeability during systemic and pulmonary inflammation in mice

BACKGROUND: Increased vascular permeability is a pathophysiological hallmark of sepsis and results in increased transcapillary leakage of plasma fluid, hypovolemia, and interstitial edema formation. 6% hydroxyethyl starch (HES 130/0.4) is commonly used to treat hypovolemia to maintain adequate organ...

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Detalles Bibliográficos
Autores principales:	Margraf, Andreas, Herter, Jan M., Kühne, Katharina, Stadtmann, Anika, Ermert, Thomas, Wenk, Manuel, Meersch, Melanie, Van Aken, Hugo, Zarbock, Alexander, Rossaint, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930811/ https://www.ncbi.nlm.nih.gov/pubmed/29716625 http://dx.doi.org/10.1186/s13054-017-1846-3

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