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A case report of spontaneous abortion caused by Brucella melitensis biovar 3

BACKGROUND: Brucellosis is a worldwide zoonotic disease caused by Brucella spp. Brucella invades the body through the skin mucosa, digestive tract, and respiratory tract. However, only a few studies on human spontaneous abortion attributable to Brucella have been reported. In this work, the patient...

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Autores principales: Yang, Hong-Xia, Feng, Jun-Jun, Zhang, Qiu-Xiang, Hao, Rui-E, Yao, Su-Xia, Zhao, Rong, Piao, Dong-Ri, Cui, Bu-Yun, Jiang, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930816/
https://www.ncbi.nlm.nih.gov/pubmed/29716658
http://dx.doi.org/10.1186/s40249-018-0411-x
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author Yang, Hong-Xia
Feng, Jun-Jun
Zhang, Qiu-Xiang
Hao, Rui-E
Yao, Su-Xia
Zhao, Rong
Piao, Dong-Ri
Cui, Bu-Yun
Jiang, Hai
author_facet Yang, Hong-Xia
Feng, Jun-Jun
Zhang, Qiu-Xiang
Hao, Rui-E
Yao, Su-Xia
Zhao, Rong
Piao, Dong-Ri
Cui, Bu-Yun
Jiang, Hai
author_sort Yang, Hong-Xia
collection PubMed
description BACKGROUND: Brucellosis is a worldwide zoonotic disease caused by Brucella spp. Brucella invades the body through the skin mucosa, digestive tract, and respiratory tract. However, only a few studies on human spontaneous abortion attributable to Brucella have been reported. In this work, the patient living in Shanxi Province in China who had suffered a spontaneous abortion was underwent pathogen detection and Brucella melitensis biovar 3 was identified. CASE PRESENTATION: The patient in this study was 22 years old. On July 16, 2015, she was admitted to Shanxi Grand Hospital, Shanxi Province, China because of one day of vaginal bleeding and three days of abdominal distension accompanied by fever after five months of amenorrhea. A serum tube agglutination test for brucellosis and blood culture were positive. At the time of discharge, she was prescribed oral doxycycline (100 mg/dose, twice a day) and rifampicin (600 mg/dose, once daily) for 6 weeks as recommended by the World Health Organization (WHO). No recurrence was observed during the six months of follow-up after the cessation of antibiotic treatment. CONCLUSIONS: This is the first reported case of miscarriage resulting from Brucella melitensis biovar 3 isolated from a pregnant woman who was infected through unpasteurized milk in China. Brucellosis infection was overlooked in the Maternity Hospital because of physician unawareness. Early recognition and prompt treatment of brucellosis infection are crucial for a successful outcome in pregnancy. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s40249-018-0411-x) contains supplementary material, which is available to authorized users.
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spelling pubmed-59308162018-05-09 A case report of spontaneous abortion caused by Brucella melitensis biovar 3 Yang, Hong-Xia Feng, Jun-Jun Zhang, Qiu-Xiang Hao, Rui-E Yao, Su-Xia Zhao, Rong Piao, Dong-Ri Cui, Bu-Yun Jiang, Hai Infect Dis Poverty Case Report BACKGROUND: Brucellosis is a worldwide zoonotic disease caused by Brucella spp. Brucella invades the body through the skin mucosa, digestive tract, and respiratory tract. However, only a few studies on human spontaneous abortion attributable to Brucella have been reported. In this work, the patient living in Shanxi Province in China who had suffered a spontaneous abortion was underwent pathogen detection and Brucella melitensis biovar 3 was identified. CASE PRESENTATION: The patient in this study was 22 years old. On July 16, 2015, she was admitted to Shanxi Grand Hospital, Shanxi Province, China because of one day of vaginal bleeding and three days of abdominal distension accompanied by fever after five months of amenorrhea. A serum tube agglutination test for brucellosis and blood culture were positive. At the time of discharge, she was prescribed oral doxycycline (100 mg/dose, twice a day) and rifampicin (600 mg/dose, once daily) for 6 weeks as recommended by the World Health Organization (WHO). No recurrence was observed during the six months of follow-up after the cessation of antibiotic treatment. CONCLUSIONS: This is the first reported case of miscarriage resulting from Brucella melitensis biovar 3 isolated from a pregnant woman who was infected through unpasteurized milk in China. Brucellosis infection was overlooked in the Maternity Hospital because of physician unawareness. Early recognition and prompt treatment of brucellosis infection are crucial for a successful outcome in pregnancy. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s40249-018-0411-x) contains supplementary material, which is available to authorized users. BioMed Central 2018-05-02 /pmc/articles/PMC5930816/ /pubmed/29716658 http://dx.doi.org/10.1186/s40249-018-0411-x Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Yang, Hong-Xia
Feng, Jun-Jun
Zhang, Qiu-Xiang
Hao, Rui-E
Yao, Su-Xia
Zhao, Rong
Piao, Dong-Ri
Cui, Bu-Yun
Jiang, Hai
A case report of spontaneous abortion caused by Brucella melitensis biovar 3
title A case report of spontaneous abortion caused by Brucella melitensis biovar 3
title_full A case report of spontaneous abortion caused by Brucella melitensis biovar 3
title_fullStr A case report of spontaneous abortion caused by Brucella melitensis biovar 3
title_full_unstemmed A case report of spontaneous abortion caused by Brucella melitensis biovar 3
title_short A case report of spontaneous abortion caused by Brucella melitensis biovar 3
title_sort case report of spontaneous abortion caused by brucella melitensis biovar 3
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930816/
https://www.ncbi.nlm.nih.gov/pubmed/29716658
http://dx.doi.org/10.1186/s40249-018-0411-x
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