A subset of mobilized human hematopoietic stem cells express germ layer lineage genes which can be modulated by culture conditions

BACKGROUND: Adult bone marrow contains stem cells that replenish the myeloid and lymphoid lineages. A subset of human and mouse CD34(+) bone marrow stem cells can be propagated in culture to autonomously express embryonic stem cell genes and embryonic germ layer lineage genes. The current study was...

Descripción completa

Detalles Bibliográficos
Autores principales: Makar, Tapas, Nimmagadda, Vamshi K., Guda, Poornachander R., Hampton, Brian, Huang, Weiliang, Kane, Maureen A., Fishman, Paul S., Pessac, Bernard, Bever, Christopher T., Trisler, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930965/
https://www.ncbi.nlm.nih.gov/pubmed/29720239
http://dx.doi.org/10.1186/s13287-018-0858-5

Ejemplares similares

Ejemplares similares