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Mediator complex (MED) 7: a biomarker associated with good prognosis in invasive breast cancer, especially ER+ luminal subtypes
BACKGROUND: Mediator complex (MED) proteins have a key role in transcriptional regulation, some interacting with the oestrogen receptor (ER). Interrogation of the METABRIC cohort suggested that MED7 may regulate lymphovascular invasion (LVI). Thus MED7 expression was assessed in large breast cancer...
Autores principales: | Joseph, Chitra, Macnamara, Olivia, Craze, Madeleine, Russell, Roslin, Provenzano, Elena, Nolan, Christopher C., Diez-Rodriguez, Maria, Sonbul, Sultan N., Aleskandarany, Mohammed A., Green, Andrew R., Rakha, Emad A., Ellis, Ian O., Mukherjee, Abhik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931067/ https://www.ncbi.nlm.nih.gov/pubmed/29588513 http://dx.doi.org/10.1038/s41416-018-0041-x |
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