PD-1 expression by tumor-associated macrophages inhibits phagocytosis and tumor immunity

Programmed cell death protein 1 (PD-1) is an immune checkpoint receptor that is upregulated on activated T cells to induce immune tolerance.(1,2) Tumor cells frequently overexpress the ligand for PD-1, programmed cell death ligand 1 (PD-L1), facilitating escape from the immune system.(3,4) Monoclona...

Descripción completa

Detalles Bibliográficos
Autores principales: Gordon, Sydney R., Maute, Roy L., Dulken, Ben W., Hutter, Gregor, George, Benson M., McCracken, Melissa N., Gupta, Rohit, Tsai, Jonathan M., Sinha, Rahul, Corey, Daniel, Ring, Aaron M., Connolly, Andrew J., Weissman, Irving L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931375/
https://www.ncbi.nlm.nih.gov/pubmed/28514441
http://dx.doi.org/10.1038/nature22396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931375/
https://www.ncbi.nlm.nih.gov/pubmed/28514441
http://dx.doi.org/10.1038/nature22396

Ejemplares similares