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A20 regulates canonical wnt-signaling through an interaction with RIPK4

A20 is a ubiquitin-editing enzyme that is known to regulate inflammatory signaling and cell death. However, A20 mutations are also frequently found in multiple malignancies suggesting a potential role as a tumor suppressor as well. We recently described a novel role for A20 in regulating the wnt-bet...

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Detalles Bibliográficos
Autores principales: Nakamura, Brooke N., Glazier, Alison, Kattah, Michael G., Duong, Bao, Jia, Yanxia, Campo, Daniel, Shao, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931457/
https://www.ncbi.nlm.nih.gov/pubmed/29718933
http://dx.doi.org/10.1371/journal.pone.0195893